WHO Guidelines

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TVolume 1 of the IAC-IARC Reporting Systems for Cytopathology is a groundbreaking new publication that provides a comprehensive synthesis of the published evidence and the practice of cytopathology. It is linked to the WHO Classification of Tumours series, now in its 5th edition. This series is the first of its kind to provide an up-to-date, authoritative reference on the field of cytopathology. It is a joint project of the International Academy of Cytology (IAC) and the International Agency for Research on Cancer (IARC), a specialized agency of the World Health Organization (WHO). This volume is a comprehensive resource for practitioners, researchers, and educators, covering the entire range of cytopathology, from basic principles to advanced techniques. It contains practical guidance on both the diagnosis and management of cytopathologic specimens. Volume 1 of the IAC-IARC Reporting Systems for Cytopathology is the first of its kind to bring together the published evidence and the practice of cytopathology. This groundbreaking publication provides a comprehensive synthesis of the field, linking it to the WHO Classification of Tumours series, now in its fifth edition. It is a collaborative project between the International Academy of Cytology (IAC) and the International Agency for Research on Cancer (IARC), a specialized agency of the World Health Organization (WHO). This volume is an invaluable resource for practitioners, researchers, and educators, covering the entire range of cytopathology, from basic principles to advanced techniques. It includes practical guidance on the diagnosis and management of cytopathologic specimens. It is a must-have reference for anyone working in the field of cytopathology.

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Cytopathologists have a unique way of looking at tumors, requiring specialized reporting systems that present key diagnostic cytopathological features in standardized reports and hierarchical categories. These categories must also be connected to diagnostic management recommendations in order to improve communication with clinicians and provide better patient care. It is essential for these reporting systems to be truly international in order to accommodate patients worldwide and various medically resourced settings.

What are the key features of this first edition of the series?

This volume is an essential resource for standardizing diagnostic cytopathology practice around the world. It provides a platform for translating cytopathology research into clinical practice. Each tumour type is listed with a set of diagnostic categories and described with precise, uniform language. The diagnostic criteria represent an international consensus, backed by data evaluated and discussed by experts in the field. Lesion-specific sections contain subsections discussing the differential diagnosis of cytopathological features that are applicable in all settings, including low-resource ones. Additionally, a subsection explains the best-practice use of ancillary testing (including next-generation sequencing) on cytopathology samples.

This volume

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  • Contributors from all over the world, with a wealth of international experience, are bringing their expertise to bear on the project. They are offering a unique perspective and helping to create a truly global product. HTML syntax and grammar issues are being fixed and the content is being rewritten to ensure it ranks higher than other sites. The focus is on creating text that is in fluent English, written in an active voice, and free of typos. HTML syntax has been corrected to ensure the structure of the text is optimal and clear for readers.
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Online version

  • The content of this new, innovative, and comprehensive cytopathology reporting series is also available in a convenient digital format, at https://tumourclassification.iarc.who.int

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